| ACTIVE | PLAYER | TITLES |
|---|---|---|
| Chris Evert Lloyd | 5 | |
| Gabriela Sabatini | 4 | |
| Conchita Martínez | 4 | |
| Serena Williams | 4 | |
| Maria Sharapova | 3 | |
| A | Iga Świątek | 3 |
| Monica Seles | 2 | |
| Amélie Mauresmo | 2 | |
| Martina Hingis | 2 | |
| Jelena Janković | 2 | |
| A | Elina Svitolina | 2 |
| Julie Heldman | 1 | |
| Billie Jean King | 1 | |
| Virginia Wade | 1 | |
| Linda Tuero | 1 | |
| Evonne Goolagong | 1 | |
| Mima Jaušovec | 1 | |
| Janet Newberry | 1 | |
| Regina Maršíková | 1 | |
| Tracy Austin | 1 | |
| Andrea Temesvári | 1 | |
| Manuela Maleeva | 1 | |
| Raffaella Reggi | 1 | |
| Steffi Graf | 1 | |
| Mary Pierce | 1 | |
| Venus Williams | 1 | |
| Jelena Dokić | 1 | |
| Kim Clijsters | 1 | |
| Dinara Safina | 1 | |
| María José Martínez Sánchez | 1 | |
| A | Karolína Plíšková | 1 |
| A | Jasmine Paolini (Current) | 1 |
| Simona Halep | 1 | |
| A | Elena Rybakina | 1 |
Table: From 1969 onward, List of Most Internazionali BNL d’Italia Titles, WTA 1000 Women, Rome, Italy, Tennis, Ranked.