| ACTIVE | PLAYER | TITLES |
|---|---|---|
| A | Iva Jovic (Current) | 1 |
| A | Jessica Pegula | 1 |
| A | Maria Sakkari | 1 |
| A | Magdalena Fręch | 1 |
Table: From 2022 onward, List of Most Guadalajara Open Akron presented by Santander Titles, WTA 500 Women, Mexico, Tennis, Ranked.
*Tournament has shifted between WTA 1000 and WTA 500.