| ACTIVE | PLAYER | TITLES |
|---|---|---|
| A | Anastasia Pavlyuchenkova | 4 |
| Garbiñe Muguruza | 2 | |
| A | Leylah Fernandez | 2 |
| Marion Bartoli | 1 | |
| A | Tímea Babos | 1 |
| Ana Ivanovic | 1 | |
| Timea Bacsinszky | 1 | |
| A | Heather Watson | 1 |
| A | Elina Svitolina | 1 |
| A | Donna Vekić | 1 |
| A | Linda Nosková | 1 |
Table: From 2009 onward, List of Most Abierto GNP Seguros Titles, WTA 500 Women, Monterrey, Mexico, Tennis, Ranked.
*Tournament has shifted between WTA 250 and WTA 500.