| ACTIVE | PLAYER | TITLES |
|---|---|---|
| Serena Williams | 8 | |
| Steffi Graf | 5 | |
| Venus Williams | 3 | |
| A | Victoria Azarenka | 3 |
| A | Aryna Sabalenka (Current) | 2 |
| Monica Seles | 2 | |
| Arantxa Sánchez Vicario | 2 | |
| Martina Hingis | 2 | |
| Kim Clijsters | 2 | |
| Ashleigh Barty | 2 | |
| Martina Navratilova | 1 | |
| Chris Evert | 1 | |
| Gabriela Sabatini | 1 | |
| Svetlana Kuznetsova | 1 | |
| Agnieszka Radwańska | 1 | |
| Johanna Konta | 1 | |
| A | Sloane Stephens | 1 |
| A | Iga Świątek | 1 |
| Petra Kvitová | 1 | |
| A | Danielle Collins | 1 |
Table: From 1985 onward, List of Most Miami Open presented by Itau Titles, WTA 1000 Women, United States of America, Tennis, Ranked.