| ACTIVE | PLAYER | TITLES |
|---|---|---|
| A | Roberto Bautista Agut | 1 |
| A | Ugo Humbert | 1 |
| A | Jannik Sinner | 1 |
| A | Félix Auger-Aliassime | 1 |
| A | Alexander Bublik | 1 |
| A | Kyle Edmund | 1 |
| Andy Murray | 1 | |
| Richard Gasquet | 1 | |
| Jo-Wilfried Tsonga | 1 |
Table: From 2016 onward, List of Most European Open titles, ATP 250, Brussels, Belgium, Men, Tennis, Ranked.