| ACTIVE | PLAYER | TITLES |
|---|---|---|
| Andre Agassi | 6 | |
| A | Novak Djokovic | 6 |
| Roger Federer | 4 | |
| Pete Sampras | 3 | |
| Andy Murray | 2 | |
| Ivan Lendl | 2 | |
| Andy Roddick | 2 | |
| A | Jannik Sinner | 1 |
| A | Hubert Hurkacz | 1 |
| A | Carlos Alcaraz Garfia | 1 |
| A | Daniil Medvedev | 1 |
| A | Jakub Mensik | 1 |
| Tim Mayotte | 1 | |
| Miloslav Mecir | 1 | |
| Mats Wilander | 1 | |
| Jim Courier | 1 | |
| Michael Chang | 1 | |
| Thomas Muster | 1 | |
| Marcelo Rios | 1 | |
| Richard Krajicek | 1 | |
| Nikolay Davydenko | 1 | |
| John Isner | 1 |
Table: From 1985 onward, List of Most Miami Open ATP Masters 1000 Titles Men, presented by itau, United States of America, Tennis, Ranked.